RNAseq, scRNAseq, metabolic modeling, systems biology
Leif has a PhD in Systems biology from Chalmers University of Technology and an engineering background in biotechnology. During his graduate years he focused on biological interpretation of high-throughput data (through method development of gene-set analysis and with an interest in visualization). He also has experience working with genome-scale metabolic models and reconstructed the metabolic network of skeletal myocytes, through integrative anlaysis of transcriptome and proteome data. This network model was used, together with RNA-seq data, to gain insight into the effects of type 2 diabetes on human skeletal muscle.
He has developed two tools:
Leif joined NBIS in 2016 as part of the bioinformatics long term support team and the systems biology facility. His main experience lies within transcriptome analysis (microarrays and RNA-seq) and metabolism. Coding in R, bash, Python, Matlab.