Biography
Mun-Gwan Hong studied genetic epidemiology for his Ph.D. in the department of medical epidemiolog and biostatistics at Karolinska Institutet. After Ph.D., He worked in plasma profiling facility at SciLifeLab analysing the proteomic data. He has been involved in various omics studies, which span genomics, transcriptomics, proteomics and metabolomics. He also developed bioinformatics/analytical tools such as ProxyGeneLD, one of first tools to convert GWAS results to gene-level for gene-set enrichment analysis (PMID=19408013). Recently, combining genomic and proteomic data, he showed an analytical approach that has possiblity to zoom-in an associated spot in a protein with a clinical trait (PMID=32737166).
Mun-Gwan is working in Health and Clinical research support team at NBIS.
Publications
- Nazziwa, J., Freyhult, E., Hong, MG. et al. Dynamics of the blood plasma proteome during hyperacute HIV-1 infection. Nat Commun 15, 10593 (2024). https://doi.org/10.1038/s41467-024-54848-0
- Johansson E, Nazziwa J, Freyhult E, Hong MG, Lindman J, Neptin M, Karlson S, Rezeli M, Biague AJ, Medstrand P, Månsson F, Norrgren H, Esbjörnsson J, Jansson M; SWEGUB CORE group.(2024) HIV-2 mediated effects on target and bystander cells induce plasma proteome remodelling. iScience 27:109344. https://doi.org/10.1016/j.isci.2024.109344
- Lindelöf, L., Rantapää-Dahlqvist, S., Lundtoft, C., ..., Hong, M.-G., … Eriksson, O. (2024). A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile. Journal of Autoimmunity, 143, 103166. https://doi.org/10.1016/j.jaut.2023.103166
- Grahn, O., Holmgren, K., Hong, M. G., Sund, M., & Rutegård, M. (2024). Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study. BJS open, 8(1), zrae004. https://doi.org/10.1093/bjsopen/zrae004
- Cederroth, C.R., Hong, MG., Freydin, M.B. et al. Screening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus. JARO 24, 593–606 (2023). https://doi.org/10.1007/s10162-023-00920-3
- Vats, S., Sundquist, K., Li, Y., Wang, X., Hong, M., Sundquist, J., Zarrouk, M., Gottsäter, A., Memon, A.A., 2023. Characterization of the Mitochondrial Genetic Landscape in Abdominal Aortic Aneurysm. Journal of the American Heart Association 12, e029248. https://doi.org/10.1161/JAHA.122.029248
- Li, Y., Sundquist, K., Vats, S., Hong, M.-G., Wang, X., Chen, Y., Hedelius, A., Saal, L.H., Sundquist, J., Memon, A.A., 2023. Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer. Journal of Translational Medicine 21, 696. https://doi.org/10.1186/s12967-023-04534-4
